45yr old Female with Severe Anemia

45 yr old female with Severe Anemia
Name- K. Medha Reddy
Roll.no- 51
Batch-2017



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CASE:
Icu bed 2 

45 year old female who is a housewife survived with 3 kids came to casualty with complaints of Vomitings ( food particle as content , non bilious , non projectile ) Since yesterday there were 10 episodes 
- C/O giddiness 


Hopi:- Patient was apparently assymptomatic 1 month back then she had decreased appetite since 1 month 
- C/O weight loss since 1 month 
- C/O Shortness of breath ( grade 2 - grade 3 ) according to NYHA Classification, not associated with Orthopnea / PND
- H/O Heavy bleeding since 10 days (3-4 pads/day) 
- C/O B/L Pedal edema since 10 days 
 
Past history :- 
- H/O similar complaints in the past diagnosed with megaloblastic anemia in the year 2007 
- H/O Hemorrhoids in the year 2014
- H/O Recurrent Blood Transfusion since 2014

- Not a k/c/o DM/ HM/ Asthma / Epilepsy

Personal history:-
Married female 
Appetite - Normal
Diet :- mixed 
Bowels:- regular
Micturition:- normal 
- No addictions 

Family history:- Not significant 

General examination:-
Patient is conscious , coherent , cooperative
- oriented to time , place , person
 
- Pallor +
- No icterus , clubbing , cyanosis , odema, lymphadenopathy 

VITALS:-
Temp:- 98.5 
PR:- 112/min
RR:- 18/min
BP:- 90/60mmhg
SPO2:- 99%
GRBS:- 105mg %

Systemic examination:-
CVS:- S1S2 + PANSYSTOLIC Murmurs + Raised JVP
RS:- BAE + , No crepts 
P/A:- Splenomegaly + 
CNS:- Intact

Provisional diagnosis :- 
Anemia under evaluation 
? Megaloblastic anemia 

Investigations:- 
Serum LDH:- 4294 IU/L
Serum IRON:- 30 mg/dl

Serum electrolytes :-
Na:- 131 meq/L
K:- 3.9 meq/L
Cl:- 99 meq/L

Blood urea :- 18mg/dl
Creatinine :- 0.6 

CRP:- Negative 

Usg abdomen and pelvis :- 
Impression - 
mild splenomegaly 

2D ECHO:- 
Impression:- 
EF:- 60%
Rvsp:- 45mmhg 
- IVC Size ( 0.9cms ) collapsing 
- Moderate to severe MR, Mild TR + with PAH? , Trivial AR +
- NO RWMA , NO AS/MS , Sclerotic AV
- Good Lv systolic function 
- Diastolic Dysfunction ++ , No PE

LFT:-
TB:- 1.87 mg/dl
DB:- 0.42 mg/dl
AST:- 106 IU /L
ALT:- 18 IU/L
ALP:- 102 IU / L
TP:- 4.9 gm/dl
Albumin:- 2.9 gm/dl
A/G :- 1.49


Management :- 
1) Tab ZOFER 4mg IV/ SOS
2) Inj NEOMOL 100ml ( if temp greater than 101.1 )
3) Inj PAN 40mg IV/ OD
4) Monitor Vitals Hrly



SOAP NOTES 
Day 2 
ICU BED 2 

S:- 
- C/O Burning Micturition 
- No vomiting episodes
- No giddiness 
- SOB reduced 

O:- 
Patient is conscious , coherent , cooperative 
- oriented to time , place , person 
Temp:- 97.3
PR:- 104
BP:- 90/60
RR:- 18 cpm
SPO2 :- 98%
GRBS:- 104mg/dl
CVS:- S1S2 + , No murmurs
RS:- NVBS + , No crepts 
P/A :- Splenomegaly +

A:- Anemia secondary to ? nutritional deficiency ( B12) 

P:- 
1) Inj METHYLCOBALAMINE 1500mg in 50ml NS/IV / OD
2) Inj PAN 40mg IV/OD
3) Inj ZOFER4mg IV/SOS
4) Inj NEOMOL 100ml ( if temp > 101.1) 
5) Inj TRANEXAMIC ACID 1 Amp / IV/BD
6) Monitor Vitals Hrly

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