43 YEAR MALE WITH SEIZURES

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19.10.2021

43 YEAR OLD MALE WITH SEIZURES


 A 43 year old male patient came to the casuality on 18/1021 at 8:20 pm with 

c/o fever - low grade 1 episode yesterday 

C/o sudden onset of involuntary movements of rt UL and LL

with frothing +, 

LOC lasting for 10 mins with

 post-icteal confusion +

PAST HISTORY: 




43yr/male, unmarried, born to non-consanguineous marriage was diagnosed with poliomyelitis at age < 5 yrs , studied upto 6th standard and stopped school due to decreased attention and ? Memory 


impairment , walked with support.


He attained all milestones normally.


He was given the job of taking care of cattle till his father expired around 5 yrs back.

Just before this he behaved unusually, talking to himself, wandering around, behaved aggressively for 1 week and was taken to yerragadda and was started on anti psychotics.

He was then made to stay at home, able to perform his own activities. 


Patient was asymptomatic till 1 day ago, when he developed fever which was low grade, decreased on medication.

At 3:00 pm yesterday , after he finished having lunch, Pt suddenly developed one episode of Rt sided UL and LL involuntary movements with loss of consciousness for 10 mins, regained spontaneously; did not talk after that.

Following that he had 2 more episodes, each lasting for 2-3 mins, with one episode of vomiting.

He was treated outside with 

inj Levipil 2g IV/ stat, catheterised and referred here.

Not a k/c/o HTN, DM 


VITALS ON ADMISSION:


Temp- afebrile

Pulse- 92 bpm

BP- 140/90 mmhg

RR- 18 cpm

Spo2- 98% at RA

GRBS- 137 mg/dl


ON EXAMINATION:

 



CVS- S1 S2 +. No murmurs 

RS- NVBS. No crepts 

P/A- soft 

CNS-

Drowsy but arousable

Speech- no response 

GCS- G2 V2 M5

Pupils -NS sluggish r/n to light 

Conjunctival reflex +

Corneal reflex +


                  Rt.                  Lt

Tone

       UL  Increased          N


       LL  Increased.         N

Power

       UL.     4/5.           4/5 


       LL.      3/5           3/5

Reflexes

             B.    2+          2+

             T      2+         2+

             S.      -           2+

             A.     -            -

             K.     -             -

             P.      ^          Mute


INVESTIGATIONS:

ECG:


CHEST X-RAY:

MRI BRAIN:

Diagnosis:

Focal seizures ( Rt side ) with secondary generalisation  secondary to cortical venous sinus thrombosis 

with

H/o ? Psychosis 

( on anti-psychotics)


TREATMENT IN HOSPITAL:

Ryles catheterisation

Inj lorezepam 2 cc/IV/ sos 

Inj mannitol 100 ml IV/TID

W/H Antipsychotics 

RT feeds- 50 ml milk 2nd hourly.


Day 2:

Inj mannitol 100 ml / IV/ TID

Inj Levipil 1 gm/ IV/ BD

Inj Lorazepam 2 cc/ IV / SOS 

RT feeds- 50 ml water 2nd hourly 

                100 ml milk 4th hourly 

Inj Monocef 1g IV/ BD

inj Enoxaparin 40 mg every 12th hourly


Day 3
 Pt was having constant fever spikes (100-101 F) since yesterday night and GCS -3/15 . No response to deep painful stimulus. pulse rate intially was 52-58 bpm (bradycardia) for sometime. Later pt had tachycardia with pulse rate of 160-170 Bpm.(sinus tachy) .BP -160/100 mmhg

- INJ PCM 1gm was given twice and tepid sponging ,ice packs were placed. Heart rate decreased to 150 bpm.

At around 4:00 am , pt saturations started falling and spo2 -46% on RA.

Central pulse was present. But there was no spontaneous breathing .

So immediately ambu was done with high flow oxygen. Oral suctioning was done .

After adequate pre-oxygenation , pt was Intubated with 7 mm ET tube and connected to mechanical ventilator .

ACMV VC MODE : RR-14 /min ; FIO2- 100% ; 

VT- 480 ml ; peep-5 cm of h20 .

Post intubation vitals : 
 BP- 120/70 mmhg - on NA -6ml/hr

PR- 116 bpm ; regular.
SPO2-. 98% ;
 RR- 14 cpm
CVS -S1, S2 PRESENT
RS- BAE present . B/L coarse crepts present.


post intubation ABG : 

ABG : ph - 7.18
pco2- 59
po2- 51
sO2- 73.8 %

hco3- 18.3



POST INTUBATION X ray


2D ECHO: 

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